How much of a pay downgrade would you accept?

I have an opportunity to jump ship from my current job that has just been getting worse and worse for employees, but pays pretty well. I’d be going to a smaller company sponsor-side (I’m currently CRO) but I’d be taking about 5-10K pay decrease to move to the new place. I’m just wondering, in general, how much is a better environment worth to you all? I’m also just kinda assuming the environment is better than what I have now based on company reviews.